I have been working with CiviCRM (Drupal and Wordpress), for around 7 years, in various organisations around Australia, from national to the local. I feel it's the perfect not-for-profit contact database and fundraising option. Always up for chat about it all.
We recommend and use CiviCRM with most of our clients, and have since 2005. It's got a fantastic collection of functionality that fits the needs of non-profit organization communications, and the CiviCRM community of developers and users is growing, broad, vibrant and responsive.
The best part? When I describe to potential new converts how all of their constituent relations (donations, membership, mass emails, etc.) can be managed with a single integrated, configurable tool, I can hear an incredible yearning at the other end of the phone.
CiviCRM is a cost-effective CRM made especially for nonprofits. Since the purpose of Drishtant is to help nonprofits to leverage technology for deeper social impact, we offer a hosted version of CiviCRM as a great way to manage relationships.